Table 1.
Spearman correlation between gut microbiota at phylum and genus levels with NAFLD-related parameters.
| Lachnospiraceae _NK4A136_group | Desulfovibrio | Alloprevotella | Alistipes | Blautia | |
|---|---|---|---|---|---|
| Serum ALT | 0.355 | 0.051 | −0.299 | 0.067 | −0.098 |
| Serum TG | 0.375* | 0.159 | −0.485** | 0.106 | −0.241 |
| Serum TC | 0.403* | 0.177 | −0.572** | −0.033 | −0.543** |
| Serum HDL-C | 0.389* | 0.240 | −0.521** | −0.036 | −0.507** |
| Serum LDL-C | 0.466** | 0.269 | −0.605** | 0.125 | −0.396* |
| Serum FBG | 0.065 | 0.336 | −0.478** | 0.094 | −0.350 |
| Serum INS | 0.224 | −0.029 | −0.534** | 0.052 | −0.071 |
| HOMA-IR | 0.155 | 0.127 | −0.607** | 0.087 | −0.212 |
| Srum LPS | 0.401* | 0.092 | −0.399 | 0.206 | −0.096 |
| Liver TG | 0.232* | 0.214* | −0.376** | 0.081 | −0.441* |
| Liver TNF-α | 0.312 | −0.018* | −0.210 | 0.141 | −0.063 |
| Liver IL-6 | 0.378* | 0.424* | −0.120 | 0.334 | −0.010 |
| TLR-4 mRNA | 0.582** | 0.435 | −0.269 | 0.378* | −0.035 |
| NF-κB mRNA | 0.464** | 0.334 | −0.593** | 0.211 | −0.216 |
| NLRP3 mRNA | 0.059 | 0.367* | −0.379* | 0.219 | 0.143 |
| Caspase-1 mRNA | 0.235 | 0.282 | −0.586** | 0.325 | −0.079 |
| IL-1β mRNA | 0.124 | 0.305 | 0.133 | 0.162 | 0.406* |
*
p < 0.05;
**
p < 0.01.