. 2023 Mar 23;14:1122118. doi: 10.3389/fphar.2023.1122118

TABLE 3.

Summary of the differential metabolites identified in the serum of three Groups.

No	metabolites	HMDB ID	t_R/min	m/z	Model/Control			Ganlong/Model
No	metabolites	HMDB ID	t_R/min	m/z	VIP	FC	trend	VIP	FC	trend
ESI+
1	Dieporeticenin	HMDB0029792	0.51	573.4884	1.83	0.07	↓ ^a	1.77	4.35	↑ ^c
2	1H-Indole-3-carboxaldehyde	HMDB0029737	0.79	146.0599	1.90	0.76	↓ ^b	2.13	1.27	↑ ^c
3	Thymine	HMDB0000262	1.46	127.0503	2.14	1.72	↑ ^b	2.34	0.72	↓ ^d
4	PC (P-18:1 (11Z)/22:5 (4Z, 7Z, 10Z, 13Z, 16Z))	HMDB0011293	2.62	818.6078	2.29	3.05	↑ ^b	2.15	0.55	↓ ^c
5	PE (P-18:1 (11Z)/22:5 (4Z, 7Z, 10Z, 13Z, 16Z))	HMDB0011425	2.62	776.5596	2.04	1.96	↑ ^b	2.06	0.64	↓ ^c
6	PC (20:2 (11Z, 14Z)/20:4 (5Z, 8Z, 11Z, 14Z))	HMDB0008345	2.64	834.6009	1.69	1.37	↑ ^a	2.19	0.70	↓ ^c
7	PE (P-18:1 (9Z)/20:4 (5Z, 8Z, 11Z, 14Z))	HMDB0011451	2.65	750.5438	2.17	2.03	↑ ^b	1.84	0.68	↓ ^c
8	PE (O-16:1 (1Z)/22:6 (4Z, 7Z, 10Z, 13Z, 16Z, 19Z))	HMDB0005780	2.65	748.5291	2.37	1.89	↑ ^b	2.06	0.70	↓ ^c
9	PC (20:4 (8Z, 11Z, 14Z, 17Z)/P-18:0)	HMDB0008489	2.66	794.6076	2.34	1.89	↑ ^b	1.91	0.70	↓ ^c
10	Vaccenyl carnitine	HMDB0006351	3.31	426.3584	2.34	1.90	↑ ^b	1.96	0.85	↓ ^c
11	SM (d16:1/24:1 (15Z))	HMDB0011694	3.36	785.6528	1.70	1.34	↑ ^a	1.97	0.75	↓ ^c
12	cis-5-Tetradecenoylcarnitine	HMDB0002014	3.43	370.2948	2.14	1.73	↑ ^b	2.06	0.77	↓ ^c
13	Dodecanoylcarnitine	HMDB0002250	3.51	344.2793	1.93	1.68	↑ ^b	1.88	0.72	↓ ^c
14	Trimethylamine N-oxide	HMDB0000925	5.88	76.0762	1.94	2.97	↑ ^b	2.53	0.27	↓ ^d
15	Lysyl-Valine	HMDB0028964	9.65	246.1814	2.16	1.60	↑ ^b	2.03	0.71	↓ ^c
ESI-
16	Hexylresorcinol	HMDB0032567	0.81	193.1229	1.80	1.46	↑ ^b	1.76	0.82	↓ ^c
17	2-Furoic acid	HMDB0000617	0.82	111.0078	1.52	0.51	↓ ^a	2.07	1.77	↓ ^c
18	Maslinic acid	HMDB0002392	0.93	471.3488	2.07	4.74	↑ ^a	2.46	0.28	↓ ^c
19	Thymidine	HMDB0000273	1.36	241.0833	1.84	1.39	↑ ^b	2.05	0.83	↓ ^c
20	Malonic acid	HMDB0000691	1.42	103.0027	1.23	0.56	↓ ^a	1.80	1.70	↓ ^c
21	p-Cresol	HMDB0001858	3.11	107.0493	1.61	2.31	↑ ^a	1.72	0.48	↓ ^c

Control group, model group and Ganlong capsule treatment group (n = 6). Model group compared with normal control group.

p < 0.05.

p < 0.01. Ganlong capsule group compared with model group.

p < 0.05.

p < 0.01.