TABLE 3.

SNV changes of 10 ASD patients.

ID	Sex	Gene	Nucleotide change	Amino acid change	Type of mutation	Origin	Clinical diagnosis
ASD0046	female	ASH1L	c.8595delT	p.Gln2866fs	Frameshift	de novo	Intellectual developmental disorder, autosomal dominant 52
ASD0061	male	EP300	c.4242T>G	p.Tyr1414*	Non-sense	de novo	Menke-Hennekam syndrome 2
ASD0063	female	SCN2A	c.4550_4551del	p.Ala1517fs	Frameshift	de novo	Developmental and epileptic encephalopathy 11
ASD0134	male	ADNP	c.2156_2157insA	p.Tyr719*	Non-sense	de novo	Helsmoortel-van der Aa syndrome
ASD0148	female	SHANK3	c.4728_4740del	p.Leu1577fs	Frameshift	de novo	Phelan-McDermid syndrome
ASD0162	male	NF1	c.7395-2A>T	-	Splicing	de novo	Neurofibromatosis, type 1
ASD0219	female	PRKD1	c.41_71del	p.Leu14fs	Frameshift	de novo	Congenital heart defects and ectodermal dysplasia
ASD0221	male	SCN2A	c.605 + 1G>A	-	Splicing	de novo	Episodic ataxia type 9
ASD0294	male	PTEN	c.546dupA	p.Leu182fs	Frameshift	de novo	Macrocephaly/autism syndrome
ASD0326	male	SCN2A	c.1570C>T	p.Arg524*	Non-sense	de novo	Episodic ataxia type 9