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. 2023 Mar 23;14:866407. doi: 10.3389/fgene.2023.866407

TABLE 5.

Euclidean distances between continental groups calculated from HLA-DRB1 frequencies.

SSA vs. SSA NAF SWA EUR NEA SEA NAM SAM AUS OCE
Mean 0.226 0.263 0.300 0.270 0.328 0.441 0.624 0.608 0.567 0.459
SD 0.079 0.073 0.065 0.071 0.069 0.093 0.137 0.119 0.064 0.055
Minimum 0.058 0.109 0.140 0.119 0.203 0.276 0.239 0.382 0.384 0.304
Maximum 0.431 0.479 0.539 0.526 0.574 0.730 0.910 0.953 0.699 0.628

All intercontinental comparisons except SSAvsNAF, vs. SSAvsEUR, SSAvsSEA, vs. SSAvsOCE, and SSAvsNAM, vs. SSAvsSAM, were statistically significant (p < 0.01) in the ANOVA. AUS, australia; EUR, europe; NAF, north africa; NAM, north america; NEA, northeast asia; OCE, oceania; SAM, south america; SEA, southeast asia; SWA, southwest asia; SSA, Sub-Saharan Africa; SD, standard deviation.