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. 2023 Mar 23;11:1129187. doi: 10.3389/fbioe.2023.1129187

FIGURE 3.

FIGURE 3

AT-EVs promoted the viability, tube formation, and migration of human umbilical vein endothelial cells (HUVECs) in vitro (A) Cell viability of HUVECs incubated with different concentrations of AT-EVs for 72 h (n = 3). (B) Tube formation of HUVECs, observed under a light microscope (n = 3). Scale bar = 250 μm. (C) Migration of HUVECs after 24 h incubation with 100 μg/mL AT-EVs (n = 3). Scale bar = 250 μm. (D) Statistical analysis of tube formation of HUVECs (total branching length and number of junctions) (n = 3). (E) Statistical analysis of HUVEC migration (n = 3). n. s. no significant difference observed between groups. *p < 0.05, **p < 0.01, ***p < 0.001.