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. 2023 Mar 23;11:1129187. doi: 10.3389/fbioe.2023.1129187

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Copyright © 2023 Pan, Xu, Zheng, Wang, Chen, Fu, Liu, Chen, Xue, Zhou and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AT-EVs promoted cell proliferation, keratinocyte differentiation and migration, and angiogenesis while decreasing inflammation in vivo (A) Immunofluorescent staining of CK14 (red), CD31 (red), and Ki67 (green), representing keratinocyte differentiation and migration, angiogenesis, and cell proliferation, respectively, as well as CD68 (red), representing inflammatory cells, observed under a fluorescence microscope. Scale bar = 75 μm. (B) Statistical analysis of CD31-positive area (n = 6). (C) Statistical analysis of Ki67-positive cells (n = 6). (D) Statistical analysis of CD68-positive cells (n = 6).