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. 2023 Mar 23;14:1117438. doi: 10.3389/fendo.2023.1117438

Table 2.

Independency of muscle measurements and handgrip strength.

HGS (kg)
Measurement model 1 model 2 model 3 model 4 model 5
β P β P β P β P β P
Thigh muscle CSA (mm2) 0.503 <0.001 0.483 <0.001 0.433 <0.001 0.382 0.001 0.267 0.018
L3 trunk muscle CSA (mm2) 0.518 <0.001 0.504 <0.001 0.448 <0.001 0.402 0.001 0.227 0.062
G.Med/MinM CSA (mm2) 0.552 <0.001 0.543 <0.001 0.490 <0.001 0.454 <0.001 0.280 0.020
G.MaxM CSA (mm2) 0.383 0.001 0.349 0.005 0.304 0.007 0.221 0.079 0.079 0.500
Thigh muscle PDFF (%) -0.381 0.001 -0.372 0.001 -0.317 0.004 -0.300 0.005 -0.209 0.031
L3 trunk muscle PDFF (%) -0.443 <0.001 -0.447 <0.001 -0.353 0.003 -0.344 0.003 -0.287 0.006
G.Med/MinM PDFF (%) -0.325 0.004 -0.337 0.002 -0.202 0.100 -0.203 0.086 -0.187 0.073
G.MaxM PDFF (%) -0.351 0.002 -0.378 0.001 -0.259 0.024 -0.281 0.011 -0.194 0.053

β is the regression coefficient. Values of P < 0.05 are marked in bold.

L3 trunk, third lumbar trunk; G.Med/MinM, gluteus minimus and medius muscle; G.MaxM, gluteus maximus muscle; CSA, muscle cross-sectional area; PDFF, proton-density fat-fraction.

model 1, unadjusted; model 2, adjusted for BMI; model 3, adjusted for age; model 4, adjusted for age and BMI; model 5, adjusted for age, BMI, albumin, predialysis BUN, predialysis creatinine, and phosphorus.