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. 2023 Mar 23;14:1152117. doi: 10.3389/fimmu.2023.1152117

Table 2.

Three gene members of the IRG signature associated with 28-day mortality of sepsis patients.

Gene symbol Gene name Chromosome Coefficient P-value
HLA-DMB Major histocompatibility complex, class II, DM beta 6p21.32 -0.685 0.002
IL4R Interleukin 4 receptor 16p12.1 -0.668 0.006
LTB4R Leukotriene B4 receptor 14q12 -0.298 0.135

IRG, immune-related gene; AIC, Akaike information criterion; C-index, concordance index; CI, confidence interval.

Global P-value = 9.120e-5; AIC = 542.53, C-index (95% CI) = 0.696 (0.618 to 0.775)