Table 2.
Three gene members of the IRG signature associated with 28-day mortality of sepsis patients.
Gene symbol | Gene name | Chromosome | Coefficient | P-value |
---|---|---|---|---|
HLA-DMB | Major histocompatibility complex, class II, DM beta | 6p21.32 | -0.685 | 0.002 |
IL4R | Interleukin 4 receptor | 16p12.1 | -0.668 | 0.006 |
LTB4R | Leukotriene B4 receptor | 14q12 | -0.298 | 0.135 |
IRG, immune-related gene; AIC, Akaike information criterion; C-index, concordance index; CI, confidence interval.
Global P-value = 9.120e-5; AIC = 542.53, C-index (95% CI) = 0.696 (0.618 to 0.775)