Table 3.

Multivariable Analysis of Predictors of Statin Initiation Stratified by Calendar Year

	Before 1 Jan 2010	1 Jan 2010–1 Jan 2015	After 1 Jan 2015
Statin initiators (N)	687	529	340
Incidence rate per 1000 person-years	16.6	22.1	18.1
Hazard ratio (95% CI)
Age
● < 50	Ref.	Ref.	Ref.
● 50–59	1.31 (1.00–1.70)	1.28 (0.93–1.75)	1.80 (1.07–3.01)
● 60–69	2.03 (1.56–2.65)	1.11 (0.80–1.54)	1.85 (1.09–3.12)
● ≥ 70	1.23 (0.88–1.72)	1.14 (0.79–1.65)	1.84 (1.05–3.21)
Women	1.26 (1.07–1.47)	0.94 (0.78–1.13)	1.04 (0.82–1.30)
Education
● ≥ 17 years	Ref	Ref	Ref
● 13–16 years	1.09 (0.64–1.87)	1.34 (0.73–2.46)	1.52 (0.71–3.27)
● 10–12 years	1.26 (0.77–2.05)	1.67 (0.95–2.92)	1.67 (0.82–3.41)
● ≤ 9 years	1.17 (0.71–1.91)	1.46 (0.83–2.58)	1.80 (0.87–3.69)
● Not classified	1.72 (0.93–3.18)	0.84 (0.36–1.92)	1.58 (0.62–4.03)
Employment status
● Outside labour force	Ref.	Ref.	Ref
● Employed	1.03 (0.84–1.27)	1.20 (0.94–1.53)	1.58 (1.17–2.14)
● Unemployed	0.97 (0.65–1.45)	0.87 (0.62–1.24)	1.15 (0.73–1.79)
● Missing	0.54 (0.20–1.45)	-	-
Cohabitation status
● Alone	Ref.	Ref.	Ref
● Cohabiting	1.27 (1.09–1.48)	0.98 (0.82–1.17)	1.01 (0.80–1.26)
Metabolic syndrome-related disease	3.18 (2.72–3.73)	3.29 (2.75–3.95)	2.30 (1.85–2.88)
Cardiovascular disease	4.40 (3.75–5.15)	3.69 (3.08–4.42)	4.82 (3.86–6.02)
Decompensated cirrhosis	0.70 (0.58–0.85)	0.55 (0.44–0.68)	0.67 (0.51–0.90)