Table 2.

Median Overall Survival in Months Among WHO Grade 4 IDH-wildtype Glioblastomas by MGMT Promoter Status and Treatment

	MGMT Promoter Unmethylated (n = 2849)		MGMT Promoter Methylated (n = 2015)
	Median OS	(95CI)	Median OS	(95CI)
Overall	12.4	12.0–12.9	17.1	16.1–18.6
Therapy
No chemo, no RT	2.8	2.4–3.3	2.6	2.1–3.2
RT, no chemo	7.3	6.0–7.9	7.5	5.5–9.5
Chemo, no RT	7.9	6.6–12.3	10.0	7.5–13.0
Chemo & RT	14.1	13.7–14.7	21.8	20.3–23.2

Abbreviations: Chemo, chemotherapy; OS, overall survival; RT, radiotherapy; 95CI, 95% confidence interval.