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. 2022 Oct 10;25(4):635–647. doi: 10.1093/neuonc/noac231

Figure 1.

Figure 1.

HOXA3 is upregulated in GBM and predicts poor prognosis. (A-B) Representative immunofluorescence images and quantifications of HOXA3 staining in TMA (scale bar: 20 μm). (C) Analyses of French database about HOXA3 expression in normal tissues, low-grade glioma, and GBM. (D) qRT-PCR analysis of HOXA3 mRNA levels in our local GBM and normal tissues. (E) Analyses of HOXA3 expression in AgilenG4502A TCGA GBM database. (F) Percent overall survival from our local GBM patients with high HOXA3 expression or low HOXA3. Shown is a Kaplan–Meier curve. (G) qRT-PCR analysis of HOXA3 mRNA levels in normal glia cells, GBM cell lines, and primary GBM cells. All data were analyzed with Student’s t-test and shown as means and SD, **P < .01, ***P < .001.