Table 2.
Study parameters and comparison between parameters during acute COVID-19 (acute) and follow-up (FU).
| Acute |
FU |
P-value* | |
|---|---|---|---|
| Median (IQR) | Median (IQR) | ||
| Neopterin [nmol/L] | 29.17 (17.89-44.75) | 9.09 (8.0-13.35) | <.001 |
| Kyn [µmol/L] | 3.42 (2.35-4.05) | 2.32 (1.94-2.49) | .004 |
| Trp [µmol/L] | 43.29 (37.74-52.17) | 52.80 (46.49-60.55) | .024 |
| Phe [µmol/L] | 126.57 (113.24-150.35) | 68.91 (62.59-80.42) | <.001 |
| Tyr [µmol/L] | 64.99 (59.16-74.54) | 58.34 (53.06-72.88) | .063 |
| Kyn/Trp [µmol/mmol] | 67.36 (53.63-92.64) | 41.01 (34.42-56.79) | <.001 |
| Phe/Tyr [µmol/µmol] | 1.91 (1.59-2.15) | 1.11 (0.99-1.36) | <.001 |
| Nitrite [µmol/L] | 22.66 (12.85-41.14) | 29.62 (12.69-96.96) | n.s. |
| WBC [G/L] | 6.3 (4.9-8.6) | 6.6 (5.38-7.43) | n.s. |
| Segmented neutrophils [%] | 78.0 (60.0-85.5) | 60.65 (53.33-70.28) | .002 |
| Monocytes [%] | 5.1 (2.8-9.4) | 8.1 (6.23-9.33) | n.s. |
| Eosinophil granulocytes [%] | 0.2 (0.0-1.4) | 1.5 (0.93-2.58) | <.001 |
| Lymphocytes [% of WBC] | 15 (9.4-26.3) | 26 (21.08-32.58) | .001 |
| Lymphocytes [G/L] | 0.95 (0.58-1.25) | 1.58 (1.23-2.14) | <.001 |
| Fibrinogen [mg/dL] | 582 (450-637.5) | 300 (256-387.8) | <.001 |
| CRP [mg/dL] | 10.93 (2.72-19.04) | 0.16 (0.06-0.61) | <.001 |
| Procalcitonin [µg/L] | 0.2 (0.08-0.5) | 0.06 (0.06-0.07) | <.001 |
| IL-6 [ng/L] | 85.8 (21.2-205.4) | 2.75 (1.5-7.43) | <.001 |
| Hemoglobin [g/L] | 123 (116-137) | 132.5 (122-140.75) | n.s. |
| RBC [T/L] | 3.96 (3.71-4.48) | 4.24 (3.96-4.6) | n.s. |
| MCV [fL] | 89 (86.6-92.4) | 91.4 (89.78-94.18) | <.001 |
| MCH [pg] | 30.9 (30.2-31.6) | 30.45 (29.8-31.63) | n.s. |
| Folate [µg/L] | 10.6 (5.43-13.25) | 6.5 (4.43-9.6) | n.s. |
| Vitamin B12 [pmol/mL] | 396.5 (291.25-654) | 285 (207.75-372.5) | .040 |
| Total serum iron [µmol/L] | 4.35 (3.23-5.7) | 15.7 (9.08-19.95) | <.001 |
| Ferritin [µg/L] | 973 (494-2021) | 253 (135-413.75) | <.001 |
| Transferrin [mg/dL] | 141.5 (108.75-177.25) | 234 (210.75-264) | <.001 |
| Transferrin saturation [%] | 12.5 (10-17.75) | 25.5 (13.75-35.5) | .001 |
Median values and IQR of study parameters and longitudinal comparison between certain groups.
*
P-value comparing parameters during acute COVID-19 (acute) and follow-up (FU); no significant difference (n.s.).
Lab parameters printed in bold differed significantly between acute Covid -19 infection and reconvalescence.