Table 4.
Univariate analysis of clinical characteristics for overall survival using the Cox proportional hazards model in BCLC stage C patients (n = 37)
| Parameters | Univariate analysis | P value |
|---|---|---|
| Age (years)≥ 60 vs. < 60 | 1.142 (0.405, 3.220) | 0.801 |
| Sex Male vs. Female | 0.412 (0.116, 1.1462) | 0.170 |
| BMI (kg/m2) ≥ 25 vs. < 25 | 1.019 (0.321, 3.327) | 0.975 |
| ECOG performance 1 versus 0 | 1.715 (0.619, 4.753) | 0.299 |
| HBV infection Yes vs. No | 0.466 (0.159, 1.369) | 0.165 |
| HCV infection Yes vs. No | 4.141 (1.136, 15.088) | 0.031* |
| Child-Pugh score B vs. A | 3.754 (0.418, 33.727) | 0.238 |
| AFP (ng/mL) ≥ 400 vs. < 400 | 2.674 (0.848, 8.428) | 0.093 |
| Vascular invasion Yes vs. No | 0.395 (0.110, 1.422) | 0.155 |
| Extrahepatic spread Yes vs. No | 2.335 (0.828, 6.857) | 0.109 |
| SAT volume index (cm2/m2) High vs. Low | 0.539 (0.183, 1.594) | 0.264 |
| SAT CT value (HU) High vs. Low | 2.931 (0.921, 9.324) | 0.069 |
| Group High risk vs. Low risk | 4.272 (1.405, 12.985) | 0.01* |
Abbreviations: BCLC: Barcelona Clinic Liver Cancer; BMI: Body mass index; HBV: chronic viral hepatitis B infection; HCV: hepatitis C infection; HU: Hounsfield unit; SAT: subcutaneous adipose tissue.
*
P < 0.05.