Screening of real hub genes-associated chemotherapeutic drugs. (A-F) indicates chemotherapeutic drugs that can decrease or increase the expression of the real hub genes. (A) CDC6-associated chemotherapeutic drugs, (B) PBK-associated chemotherapeutic drugs, (C) AURKA-associated chemotherapeutic drugs, (D) KIF2C-associated chemotherapeutic drugs, (E) OIP5-associated chemotherapeutic drugs, and (F) PRC1-associated chemotherapeutic drugs. Red arrows: drugs that increase the real hub genes expression, Green arrows: drug that decrease the real hub genes expression while the numbers of arrows represent the supported numbers of studies in literature.