Table 1. Baseline Characteristics of Patients With First-Ever ICH Stratified by Hematoma Locationa.
| Characteristic | Crude data | Weighted data | |||||
|---|---|---|---|---|---|---|---|
| Lobar ICH (n = 1034) | Nonlobar ICH (n = 1255) | Mean standardized difference | Lobar ICH (n = 1034) | Nonlobar ICH (n = 1255) | Mean standardized difference | ||
| Age at baseline, mean (SD), y | 75.2 (10.7) | 73.5 (11.4) | 0.1466 | 74.3 (11.1) | 74.3 (11.1) | 0.0001 | |
| Sex | |||||||
| Male | 495 (47.9) | 680 (54.2) | −0.1265 | 529.1 (51.2) | 643.1 (51.2) | −0.0014 | |
| Female | 539 (52.1) | 575 (45.8) | 0.1265 | 504.9 (48.8) | 611.9 (48.8) | 0.0014 | |
| Medical history | |||||||
| Previous ischemic stroke | 130 (12.6) | 191 (15.2) | −0.0766 | 146.9 (14.2) | 177.2 (14.1) | 0.0025 | |
| Myocardial infarction | 56 (5.4) | 58 (4.6) | 0.0364 | 50.8 (4.9) | 61.9 (4.9) | −0.0013 | |
| Peripheral artery disease | 58 (5.6) | 78 (6.2) | −0.0257 | 61.8 (6.0) | 74.8 (6.0) | 0.0006 | |
| Hypertension | 701 (67.8) | 920 (73.3) | −0.1211 | 735.2 (71.1) | 890.3 (70.9) | 0.0036 | |
| Diabetes | 131 (12.7) | 174 (13.9) | −0.0512 | 138.3 (13.4) | 168.0 (13.4) | −0.0003 | |
| Atrial fibrillation | 216 (20.9) | 273 (21.8) | −0.0509 | 225.7 (21.8) | 270.3 (21.5) | 0.0070 | |
| COPD | 283 (27.4) | 373 (29.7) | −0.0324 | 296.2 (28.6) | 358.4 (28.6) | 0.0018 | |
| Diagnoses indicative of high alcohol use | 87 (8.4) | 124 (9.9) | −0.0647 | 95.0 (9.2) | 115.8 (9.2) | −0.0014 | |
| Medication before ICHb | |||||||
| Platelet antiaggregant | 381 (36.8) | 382 (30.4) | 0.1360 | 342.1 (33.1) | 415.8 (33.1) | −0.0011 | |
| Anticoagulant | 172 (16.6) | 247 (19.7) | −0.0791 | 191.9 (18.6) | 230.8 (18.4) | 0.0044 | |
| Statin | 310 (30.0) | 370 (29.5) | 0.0109 | 305.9 (29.6) | 371.4 (29.6) | −0.0003 | |
| Antihypertensives | 482 (46.6) | 591 (47.1) | −0.0095 | 485.8 (47.0) | 588.5 (46.9) | 0.0018 | |
Abbreviations: COPD, chronic obstructive pulmonary disease; ICH, intracerebral hemorrhage.
a
Data are presented as number (percentage) of patients unless otherwise indicated.
b
According to data from the Danish National Prescription Registry and corresponding to current use defined as dispensed quantity of drug that lasted until date at onset of index ICH (or ended no later than 30 days before this date).