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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Lancet Respir Med. 2022 Aug 16;11(1):65–73. doi: 10.1016/S2213-2600(22)00251-X

Figure 1: Manhattan plots for longitudinal FVC (A) and DLCO (B) genome-wide meta-analyses.

Figure 1:

Each point represents a variant, with chromosomal position on the x axis and –log10(p value) on the y axis. The red horizontal line shows the genome-wide significance threshold of p=5 × 10−8. DLCO=diffusing capacity of the lung for carbon monoxide. FVC=forced vital capacity. PKN2-AS1=protein kinase N2 gene in introns of the antisense RNA.