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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Lancet Respir Med. 2022 Aug 16;11(1):65–73. doi: 10.1016/S2213-2600(22)00251-X

Figure 3: Region plot for the locus significantly associated with FVC decline.

Figure 3:

Each point represents a variant, with chromosomal position on the x axis and −log10(p value) on the y axis.

The dashed horizontal line shows the genome-wide significance threshold of p=5 × 10−8. Variants are coloured by linkage disequilibrium with the sentinel variant (rs115982800) depicted as a diamond. Light blue lines show the recombination rate and gene positions are shown below the x axis. The plot was created using LocusZoom.31 FVC=forced vital capacity.