Table:

Characteristics of individuals included in FVC and DLCO analyses

	Discovery GWAS			Follow-up	Total
	US	UK	UUS	CleanUP-IPF
FVC
Sample size	142	314	592	281	1329
Study centres	3	4	6	1	14
Sex
Female	34 (23∙9%)	90 (28∙7%)	143 (24∙2%)	57 (20∙3%)	324 (24∙4%)
Male	108 (76∙1%)	224 (71∙3%)	449 (75∙8%)	224 (79∙7%)	1005 (75∙6%)
Mean age at baseline, years	65∙7 (8∙3)	71∙7 (8∙2)	68∙8 (8∙0)	71∙3 (7∙4)	69∙7 (8∙2)
Total number of visits	604	1440	2516	656	5216
Mean number of visits per person	4∙3 (1∙8)	4∙6 (2∙1)	4∙3 (1∙8)	2∙3 (0∙5)	3∙9 (1∙9)
Maximum number of visits	13	12	14	3	14
Number of deaths	27 (19∙0%)	110 (35∙0%)	136 (23∙0%)	11 (3∙9%)	284 (21∙4%)
DLCO
Sample size	75	293	361	246	975
Study centres	2	4	4	1	11
Sex
Female	15 (20∙0%)	79 (27∙0%)	88 (24∙4%)	54 (22∙0%)	236 (24∙2%)
Male	60 (80∙0%)	214 (73∙0%)	273 (75∙6%)	192 (78∙1%)	739 (75∙8%)
Mean age at baseline, years	67∙5 (8∙5)	71∙5 (8∙2)	69∙2 (8∙1)	71∙1 (7∙4)	70∙2 (8∙1)
Total number of visits	251	1146	1398	566	3361
Mean number of visits per person	3∙3 (1∙4)	3∙9 (1∙7)	3∙9 (1∙7)	2∙3 (0∙5)	3∙4 (1∙7)
Maximum number of visits	7	11	13	3	13
Number of deaths	17 (22∙7%)	94 (32∙1%)	112 (31∙0%)	9 (3∙7%)	232 (23∙8%)

Data are n, n (%), or mean (SD). CleanUP-IPF=Clinical Efficacy of Antimicrobial Therapy Strategy Using Pragmatic Design in Idiopathic Pulmonary Fibrosis study. DLCO=diffusing capacity of the lung for carbon monoxide. FVC=forced vital capacity. GWAS=genome-wide association study. USS=US, UK, and Spain.