Skip to main content
. 2023 Mar 8;8(5):e166848. doi: 10.1172/jci.insight.166848

Figure 11. Volcano plots and heatmaps of effect of current CD4 on the humoral immune repertoire.

Figure 11

(A and B) Adjusted volcano plots of effect of current CD4 (without nadir CD4 adjustment) on the non–SARS-CoV-2 humoral repertoire (A) among the COVID-19– cohort and SARS-CoV-2 humoral repertoire (B) among COVID-19+ cohort. Coefficients reflect the effect of a 1 SD increase in current CD4 (cells/mm3), which was Z scored for each participant. (C and D) Respective heatmaps of the volcano plot coefficients for the non–SARS-CoV-2 (C) and SARS-CoV-2 (D) humoral responses. Significance in the heatmaps is shown as FDR-corrected *P < 0.05, **P < 0.01, or ***P < 0.001.