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. Author manuscript; available in PMC: 2023 Apr 6.
Published in final edited form as: Br J Clin Pharmacol. 2022 Aug 14;88(10):4623–4632. doi: 10.1111/bcp.15477

Table 5.

Simulated Cabotegravir Trough (Ctrough)1 After First Injection and at Steady State

Ctrough after first injection median [90% prediction interval] (ug/mL) Ctrough at steady state median [90% prediction interval] (ug/mL)
Male 0.99 [0.25,2.68] 1.75 [0.62,2.68]
Female 0.76 [0.17,2.57] 2.04 [0.91,4.11]
1

For reference: CAB PA-IC90: 0.166 μg/mL; 4*PA-IC90: 0.664 μg/mL; 8*PA-IC90: 1.33 μg/mL