Table 5.
Simulated Cabotegravir Trough (Ctrough)1 After First Injection and at Steady State
Ctrough after first injection median [90% prediction interval] (ug/mL) | Ctrough at steady state median [90% prediction interval] (ug/mL) | |
---|---|---|
Male | 0.99 [0.25,2.68] | 1.75 [0.62,2.68] |
Female | 0.76 [0.17,2.57] | 2.04 [0.91,4.11] |
For reference: CAB PA-IC90: 0.166 μg/mL; 4*PA-IC90: 0.664 μg/mL; 8*PA-IC90: 1.33 μg/mL