Table 2.
Echocardiographic parameters in the cardiotoxic group
| Variables | Baseline | End | 6 m. | 9 m. | P1 | P2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LVEF | 62.44 ± 4.50 | 60.78 ± 4.51 | 58.89 ± 4.76 | 47.89 ± 3.88 | 0.085 | 0.001* | ||||||||
| LVGLS | -21.21 ± 1.59 | -20.37 ± 1.53 | -17.49 ± 1.07 | -15.22 ± 1.18 | 0.001* | 0.001* | ||||||||
| SPAP | 14.11 ± 3.82 | 14.28 ± 3.37 | 16.44 ± 4.46 | 17.56 ± 5.36 | 0.374 | 0.088 | ||||||||
| RV-S | 14.56 ± 1.79 | 13.78 ± 1.59 | 13.24 ± 1.73 | 13.04 ± 2.36 | 0.170 | 0.081 | ||||||||
| TAPSE | 1.95 ± 0.19 | 1.94 ± 0.18 | 1.90 ± 0.11 | 1.82 ± 0.13 | 0.776 | 0.069 | ||||||||
| FAC | 44.83 ± 4.44 | 44.50 ± 3.94 | 41.44 ± 4.23 | 38.00 ± 3.76 | 0.072 | 0.001* | ||||||||
| RV EDV | 86.78 ± 9.16 | 87.50 ± 8.97 | 95.78 ± 9.23 | 105.00 ± 8.98 | 0.021* | 0.001* | ||||||||
| RV ESV | 42.50 ± 5.98 | 42.89 ± 5.92 | 50.44 ± 7.01 | 61.28 ± 8.45 | 0.005* | 0.001* | ||||||||
| RV EF | 51.13 ± 3.09 | 51.12 ± 2.83 | 48.47 ± 3.59 | 43.82 ± 4.68 | 0.130 | 0.001* | ||||||||
| RV FWLS | -24.67 ± 1.27 | -24.62 ± 1.26 | -22.22 ± 1.41 | -19.23 ± 1.54 | 0.001* | 0.001* | ||||||||
| RV GLS | -22.54 ± 0.79 | -22.44 ± 0.76 | -19.53 ± 1.32 | -17.86 ± 1.33 | 0.001* | 0.001* | ||||||||
P1: Baseline values compared with 6 months
P2: Baseline values compared with 9 months
*: means significant
LVEF: left ventricle ejection fraction, LVGLS: left ventricle global longitudinal strain, SPAP: systolic pulmonary artery pressure, RV-S: right ventricle systolic wave, TAPSE: Tricuspid annular plane systolic excursion, FAC: fractional area change, RV EDV: right ventricle end-diastolic volume, RV ESV: right ventricle end-systolic volume, RV EF: right ventricle ejection fraction, RVFWLS: right ventricular free wall longitudinal strain, and RVGLS: right ventricular global longitudinal strain