Table 4.
Univariate and multivariate analysis between the cumulative dose of anthracycline and the echocardiographic parameters in the cardiotoxic group
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| ∆ RVFWLS | 0.484 (0.283–0.619) | 0.001* | 0.519 (0.319–0.759) | 0.001* |
| ∆ LVGLS | 0.627 (0.218–0.894) | 0.001* | 0.725 (0.367–0.926) | 0.009* |
| ∆ RVEDV | 1.512 (1.386–2.829) | 0.036* | 1.625 (0.237–1.805) | 0.095 |
| ∆ RVESV | 2.695 (1.365–4.841) | 0.013* | 1.828 (0.199–3.748) | 0.081 |
| ∆ RVGLS | 0.482 (0.296–0.748) | 0.028* | 0.734 (0.329–2.652) | 0.102 |
∆ : changes in the measurements between baseline and 6 months after the end of therapy
LVGLS: left ventricle global longitudinal strain, RV EDV: right ventricle end-diastolic volume, RV ESV: right ventricle end-systolic volume, RVFWLS: right ventricular free wall longitudinal strain, and RVGLS: right ventricular global longitudinal strain