Table 1.

The details of search strategy

Step	Search strategy
#1	Orthodontics.sh. OR orthodontic*
#2	(Mouthwashes.sh. OR mouthrinse* OR mouthwash* OR ((collut* OR gargle* OR rinse* OR wash*) AND (mouth* OR oral* OR dent*)
#3	Controlled Clinical Trial.pt. OR Controlled Clinical Trials as Topic.sh. OR Random Allocation.sh. OR random* OR Control Groups.sh. OR control* OR Placebos.sh. OR placebo*
#4	Review.pt. OR Case Reports.pt. OR Systematic Review.pt. OR Editorial.pt. OR Comment.pt. OR Models, Animal.sh. OR review.ti. OR systematic review.ti. OR case report.ti. OR case study.ti. OR case series.ti. OR animal model.ti. OR animal models.ti. OR mouse.ti. OR mouses.ti. OR rat.ti. OR rats.ti. OR mice.ti. OR rabbit.ti. OR rabbits.ti. OR rodent.ti. OR rodents.ti. OR beagle.ti. OR beagles.ti. OR dog.ti. OR dogs.ti. OR fish.ti. OR fishes.ti. OR swine.ti. OR swines.ti. OR pig.ti. OR pigs.ti
#5	#1 AND #2 AND #3 NOT #4

Abbreviations: sh MeSH subject headings; * Truncation symbol; pt, publication type; ti, title