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. 2023 Apr 6;22:102. doi: 10.1186/s12912-023-01243-7

Table 2.

Comparisons of the differences on the frequency, severity, and distress of symptoms within, among and between groups at baseline and post-intervention

Outcomes ChemoFreeBot
(n = 50)
mean (SD)
Routine care
(n = 50)
mean (SD)
Nurse – led education
(n = 50)
mean (SD)
F(p) ChemoFreeBot
vs.
Routine care
ChemoFreeBot
vs.
Nurse-led education
Routine care
vs.
Nurse-led education
Symptom frequency

Physical

symptoms

Baseline 2.87 ± 0.32 2.83 ± 0.29 2.98 ± 0.31 147(p < .001*) a
Post-intervention 1.36 ± 0.28 2.78 ± 0.23 2.16 ± 0.53 76.075(p < .001*) b p < .001 ** p < .001 ** p < .001**
147(p < .001*) c

Psychological

symptoms

Baseline 2.80 ± 0.38 2.76 ± 0.35 2.76 ± 0.34 443.192(p < .001*) a
Post-intervention 1.39 ± 0.40 2.00 ± 0.39 2.75 ± 0.30 63.198(p < .001*) b p < .001 ** p < .001 ** p < .001 **
137.908(p < .001*) c
Total symptoms Baseline 2.84 ± 0.33 2.89 ± 0.25 2.80 ± 0.26 778.765(p < .001*) a
Post-intervention 1.37 ± 0.30 2.10 ± 0.39 2.77 ± 0.21 97.0(p < .001*) b p < .001 ** p < .001 ** p < .001 **
230.811(p < .001*) c
Symptom severity

Physical

symptoms

Baseline 2.87 ± 0.27 2.95 ± 0.23 2.83 ± 0.22 749.679(p < .001*) a
Post-intervention 1.43 ± 0.29 2.18 ± 0.47 2.80 ± 0.20 96.440(p < .001*) b p < .001 ** p < .001 ** p < .001 **
220.462(p < .001*) c

Psychological

symptoms

Baseline 2.90 ± 0.32 2.84 ± 0.33 2.81 ± 0.36 451.251(p < .001*) a
Post-intervention 1.40 ± 0.43 2.06 ± 0.42 2.78 ± 0.33 62.137(p < .001*) b p < .001 ** p < .001 ** p < .001 **
136.740(p < .001*) c
Total symptoms Baseline 2.88 ± 0.26 2.91 ± 0.22 2.83 ± 0.22 835.079(p < .001*) a
Post-intervention 1.42 ± 0.30 2.14 ± 0.39 2.79 ± 0.21 111.596(p < .001*) b p < .001 ** p < .001 ** p < .001 **
247.734(p < .001*) c
Symptom distress

Physical

symptoms

Baseline 2.89 ± 0.26 2.86 ± 0.29 2.97 ± 0.22 209.281(P < .001*) a
Post-intervention 1.85 ± 0.40 3.00 ± 0.32 2.76 ± 0.22 77.171(p < .001*) b p < .001 ** p < .001 ** p = 1
189.680(p < .001*) c

Psychological

symptoms

Baseline 2.91 ± 0.37 2.96 ± 0.33 2.85 ± 0.34 106.564(p < .001*) a
Post-intervention 1.68 ± 0.71 2.75 ± 0.33 3.00 ± 0.34 43.003(p < .001*) b p < .001 ** p < .001 ** p = 1
168.057(p < .001*) c
Total symptoms Baseline 2.90 ± 0.27 2.93 ± 0.21 2.84 ± 0.26 219.276(p < .001*) a
Post-intervention 1.80 ± 0.43 2.78 ± 0.20 3.00 ± 0.30 80.265(p < .001*) b p < .034 ** p < .001 ** p = .642
234.146(p < .001*) c

F: Mixed design Repeated Measures ANOVA test, SD: Standard deviation, *: Statistically significant at p ≤ .05, ** Significant results after Adjustment for multiple comparisons: Bonferroni

Mixed design repeated measures ANOVA test to assess main effect of time before and after intervention a, main effect of three programs b and interaction to assess the pattern of change of each quantitative outcome variable along time by program c.

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