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. 2023 Apr 5;21:244. doi: 10.1186/s12967-023-04089-4

Fig. 1.

Fig. 1

Graphic summary of studies on the combination therapy of SRS and ICI for brain metastases by tumor types, intervention/control arms, and intervals between SRS and ICI defined as “concurrent”. A: Concurrent SRS + ICI vs. SRS; B: Concurrent SRS + ICI vs. non-Concurrent SRS + ICI; C: Concurrent SRS + ICI vs. SRS after ICI; D: Concurrent SRS + ICI vs. SRS before ICI; E: Concurrent SRS + /before ICI vs. SRS after ICI; F: Non-concurrent SRS + ICI vs. SRS; G: Concurrent SRS + ICI vs. Concurrent WBRT + ICI