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. 2022 Nov 9;29(1):e3457. doi: 10.1002/psc.3457

FIGURE 4.

FIGURE 4

(A) Sequence of BIM BH3 and derived N‐capped peptides with introduced modifications (* α‐aminoisobutyric acid, Aib). (B) Chemical structure of N‐cap and chloroacetamide modifier in 138C5. (C) Crystal structure of 138C7 covalently bound to C55 of BFL‐1 (pdb: 2vm6). (D) Sequence of ephrin‐B PDZ binding domain/NCB1 and derived covalent inhibitor TAT‐CB‐6 with modification sites. TAT refers to a HIV TAT cell penetrating peptide (CPP).