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. Author manuscript; available in PMC: 2023 Apr 6.
Published in final edited form as: Nat Aging. 2022 May 16;2(6):484–493. doi: 10.1038/s43587-022-00220-0

Extended Data Fig. 3 |. The impact of prevention of replicative senescence on epigenetic aging.

Extended Data Fig. 3 |

Measurement of EpiAge of human neonatal primary fibroblasts transduced with hTERT-expressing vectors or empty vector at various time point during their culture until senescence (S) of the control cells. DNA methylation profiles were analyzed by four different epigenetic clocks (a-d). Similar approach was employed with adult human coronary artery cells (e-h).