Table 1.
Characteristic | N | |
---|---|---|
Site, n (%) | 85 | |
- Victoria site 1 | 20 (23) | |
- Victoria site 2 | 20 (23) | |
- New South Wales (NSW) | 16 (19) | |
- Western Australia (WA) | 29 (34) | |
Age, years (mean ± SD, Range) | 85 | 66.1 ± 10.9; Range 29 – 87 |
Gender, female n (%) | 85 | 53 (62) |
Smoking status n (%) | 80 | |
Never | 29 (36) | |
Former | 49 (61) | |
Current | 2 (3) | |
BMI, kg/m2 (mean ± SD, Range) | 72 | 29.7 ± 6.0; Range 20.5 – 49.0 |
ILD type n (%) | 82 | |
- CTD-ILD | 19 (23) | |
- HP | 6 (7) | |
- IPF | 20 (24) | |
- NSIP | 14 (17) | |
- Sarcoidosis | 7 (9) | |
- Scleroderma | 1 (1) | |
- Unclassifiable ILD | 7 (9) | |
- Other | 8 (10) | |
Years since diagnosed with ILD, (mean ± SD, Range) | 79 | 5.4 ± 4.2; Range 0.5 – 25 |
ILD medications use, yes, n (%) | 85 | 63 (74) (more than one option allowed) |
Type | ||
- Methotrexate | 5 (8) | |
- Mycophenolate | 26 (41) | |
- Nintedanib | 12 (19) | |
- Pirfenidone | 8 (13) | |
- Prednisolone | 17 (27) | |
- Rituximab | 1 (2) | |
Oxygen use – currently, yes, n (%) | 81 | 14 (17) |
Pulmonary rehabilitation in last 12 months, Yes, n (%) | 80 | 17 (21) |
Lung function assessments | ||
6MWT, ma (mean ± SD, Range) | 61 | 459.7 ± 132.6; Range 150 –774 |
FVC %pred (mean ± SD, Range)a | 69 | 75.4 ± 16.7; Range 34 – 116 |
DLCO %pred (mean ± SD, Range)a | 71 | 58.1 ± 17.0; Range 21 – 102 |
Validated questionnaire scores | ||
K-BILD transformed score, (mean ± SD, Range) | 85 | 55.8 ± 12.9; Range 27.2 – 100 |
USCD-SOB score, (mean ± SD, Range) | 85 | 43.6 ± 25.0; Range 2 – 100 |
Comorbidities | ||
Main comorbidities | 85 | n (%) |
- Autoimmune rheumatological disease | 12 (14%) | |
- Chronic kidney disease | 11 (13%) | |
- Diabetes mellitus | 9 (11%) | |
- Haematological cancer (within last 5 years) | 0 (0%) | |
- Heart disease | 5 (6%) | |
- Non-haematological cancer (within last 12 months) | 1 (1%) | |
Infections and hospitalization in 2020 | ||
Tested for COVID-19 infection, yes n(%) | 85 | 35 (41) |
- Number of positive tests | 0 (0) | |
Lung infection, yes n(%) | 85 | 19 (22) |
Hospital admissionb, yes n(%) | 85 | 24 (28) |
Main reason for admission | ||
- Infection | 8 (33) | |
- Oxygen desaturation/dyspnoea | 5 (21) | |
- Lung biopsy | 3 (13) | |
- Kidney-related | 3 (13) | |
- Other | 5 (21) |
CTD-ILD Connective tissue disease-ILD, HP hypersensitive pneumonitis, IPF idiopathic pulmonary fibrosis, NSIP Nonspecific interstitial pneumonia, 6MWT 6 min walking test, FVC% pred forced vital capacity % predicted, DLCO% pred diffusing capacity for carbon monoxide % predicted, K-BILD The King’s Brief Interstitial Lung Disease, USCD-SOB The University of California San Diego Shortness of Breath
aRefers to last result prior to date when face-to-face clinic consultations changed to telehealth
bHospital admission defined as staying one or more nights