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. 2022 Sep 7;53(1):e13862. doi: 10.1111/eci.13862

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© 2022 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Forest plots showing the meta‐analysis of risk factors for cardiac implantable electronic device malfunctions associated with radiation therapy. Panel (A) comparison of neutron‐producing energies versus non‐neutron‐producing energies. Panel (B) comparison of PM/ CRT‐P versus ICD/ CRT‐D. Panel (C) comparison of maximal radiation dose at device >2 Gy versus ≤2 Gy. CI, confidence interval; CRT‐D, cardiac resynchronization therapy and defibrillator; CRT‐P, cardiac resynchronization therapy and pacing; Dmax, maximal radiation dose at device; Gy, greygray; ICD, implantable cardioverter defibrillator; PM, pacemakers; RR, risk ratio.