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SERS‐based detection generates unique Raman scattering profiles that can be used to differentiate between cancerous and normal EVs. For comparison, EVs derived from lung cancer and normal cells were analyzed using AuNPs as plasmon‐active SERS signal amplifiers. Subsequent PCA served to perform correlation analysis on SERS spectra against profiles of known cancer marker proteins. Reprinted with permission from Shin et al. (2018). Copyright 2018 American Chemical Society
