TABLE 1.

Number of participants and incident AD cases at each exam in the FHS Offspring cohort

	Examination
	1	2	3	4	5	6	7	Between 7 and 8	8	Between 8 and 9	9	10 c
Exam cycle	1971–1975	1979–1983	1983–1987	1987–1991	1991–1995	1995–1998	1998–2001		2005–2008		2011–2014	2015– Present
Attendees a	5124	3863	3873	4019	3799	3532	3539		3021		2430
Age range	5–70	17–77	18–77	22–81	26–84	29–86	33–90		40–93		46–98
Mean age	36	44	48	52	55	59	62		67		71
No. incident AD cases b	0	2	3	2	9	22	33	36	56	53	28	17

^a 702 participants with missing education information are included in the table but were excluded from the analysis.

^b 10 AD cases with missing age at onset (not included in the table) were excluded from the analysis.

^c Data for exam 10 were not included in the analysis because they are incomplete; AD cases shown were adjudicated prior to December 31, 2016.