TABLE 2.
Odds ratios (ORs) and 95% confidence intervals (CIs) of dementia in relation to traumatic brain injury (TBI) (N = 35,312)
| All‐cause dementia (n = 3292) | Alzheimer's disease (n = 1096) | Vascular dementia (n = 692) | |||||
|---|---|---|---|---|---|---|---|
| No. of subjects | OR (95% CI) a | OR (95% CI) b | OR (95% CI) a | OR (95% CI) b | OR (95% CI) a | OR (95% CI) b | |
| TBI‐free | 34226 | Reference | Reference | Reference | Reference | Reference | Reference |
| TBI | 1086 | 1.25 (1.01–1.54) | 1.27 (1.03–1.57) | 1.16 (0.83–1.63) | 1.23 (0.88–1.74) | 1.16 (0.77–1.74) | 1.10 (0.73–1.66) |
| Age of first TBI | |||||||
| ≤39 years | 285 | 0.84 (0.42–1.68) | 0.86 (0.43–1.72) | 1.25 (0.54–2.89) | 1.33 (0.57–3.11) | 0.42 (0.06–2.94) | 0.40 (0.06–2.75) |
| 40–49 years | 253 | 1.29 (0.78–2.12) | 1.34 (0.81‐2.21) | 1.05 (0.44–2.48) | 1.12 (0.47–2.66) | 1.70 (0.70–4.13) | 1.65 (0.67–4.04) |
| 50–59 years | 259 | 1.53 (1.03–2.28) | 1.55 (1.04–2.31) | 1.62 (0.86–3.04) | 1.71 (0.91–3.19) | 1.71 (0.80–3.65) | 1.64 (0.76–3.54) |
| 60–69 years | 161 | 1.68 (1.13–2.51) | 1.67 (1.12–2.49) | 1.81 (0.99–3.30) | 1.84 (1.01–3.35) | 1.00 (0.40–2.50) | 1.02 (0.41–2.56) |
| ≥70 years | 128 | 0.89 (0.58–1.37) | 0.92 (0.59–1.42) | 0.44 (0.18–1.08) | 0.47 (0.19–1.18) | 0.97 (0.46–2.08) | 0.88 (0.41–1.89) |
a
Generalized estimating equation model adjusted for age, sex, and education.
b
Generalized estimating equation model adjusted for age, sex, education, marital status, smoking status, alcohol consumption, physical activity, body mass index, type 2 diabetes, heart disease, stroke, hypertension, and dyslipidemia.