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PASTIS trial design and recruitment. A, Trial design. For Group 1, Treatment 1 was tadalafil and Treatment 2 placebo, for Group 2 vice versa. B, Recruitment to PASTIS. C, CONSORT diagram. CONSORT, Consolidated Standards of Reporting Trials; MRI, magnetic resonance imaging; PASTIS, Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease
