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. Author manuscript; available in PMC: 2023 Apr 6.
Published in final edited form as: Handb Exp Pharmacol. 2022;275:91–107. doi: 10.1007/164_2021_518

Fig. 4.

Fig. 4

The role of 5-HT3A signaling in sour taste transmission. (a) Representative chorda tympani nerve recording to various concentrations of citric acid before and 15 min after (red) i.p. injection of the 5-HT3 antagonist ondansetron (ODS; 1 mg/kg). (b) Average chorda tympani responses in WT mice to various stimuli before and after injection of ODS. The responses to acids were, in general, significantly smaller after ODS treatment. Similar results were observed with 5-HT3A knockout mice (data not shown). Data are presented as mean ± SEM. Modified from Larson et al. (2015)