Table 4.

 Mean (SD) time (months) to first relapse in patients with colorectal cancer according to intensive or control follow up

	Intensive follow up	Control follow up	Differences in means (95% CI)
Makela et al, 199517	10.0 (5.0)	15.0 (10.0)	−5.00 (−7.99 to −2.01)
Ohlsson et al, 199518	20.4 (8.0)*	24.0 (7.0)*	−3.60 (−6.45 to −0.75)
Schoemaker et al, 199819	Not stated
Pietra et al, 199820	10.3 (2.7)	20.2 (6.1)	−9.90 (−11.19 to −8.61)
Subgroup†			−8.32 (−9.41 to −7.23)
Kjeldsen et al, 199721	17.7 (8) §	26.5 (8.0) §	−8.80 (−10.25 to −7.35)
Pooled effect‡			−8.50 (−9.37 to −7.62)

^*Estimated from ranges stated. 

^†Extramural detection trials. 

^‡Extramural and intramural detection trials. 

^§Estimated from geometric curves.