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. 2023 Apr 6;18(4):e0283974. doi: 10.1371/journal.pone.0283974

Table 2. Characteristics of the clinical and laboratory progression of 295 pregnant women with PPROM according to the presence or absence of Histological Chorioamnionitis.

Variable With HCA N (%) or Mean (SD) Without HCA N (%) or Mean (SD) P
Latency period 8.16 (16.00) 9.30 (20.37) 0.005 ‡ *
Latency > 3 days 35/70 (50%) 64/176 (36.4%) 0.049 † *
Latency ≥ 5 days 30/70 (42.9%) 60/176 (34.1%) 0.198 †
Number of chorioamnionitis criteria 2.43 (1.419) 0.49 (0.803) 0.000 ‡ **
Presence of 2 or more criteria 39/54 (72.2%) 12/128 (9.4%) 0.000 ‡ **
Corticosteroid use 7/53 (13.2%) 12/128 (9.4%) 0.444 †
Corticosteroid repetition 1/72 (1.4%) 1/177 (0.6%) 0.496 §
Use of any antibiotic 19/52 (36.5%) 34/123 (27.6%) 0.242 †
AFI < 3 15/41 (36.6%) 14/85 (16.5%) 0.012 † *
Final AFI 5.506 (4.067) 7.674 (4.434) 0.006 ‡ *
Final AFI < 5 16/35 (45.7%) 24/76 (31.6%) 0.150 †
Difference Ini-Fin AFI -1.574 (3.717) -1.513 (8.150) 0.229 ‡
Difference final 2 AFI -0.139 (3.261) -0,826 (3.270) 0.772 ‡
Final FBP 8.228 (2.314) 9.333 (1.303) 0.004 ‡ *
Absent BM 4/40 (10%) 3/85 (3.5%) 0.209 §
Changed CRP (> 5) 25/36 (69.4%) 34/47 (72.3%) 0.773 †
Final CRP 49.19 (53.655) 15.20 (22.291) 0.000 ‡ **
Difference Ini-Fin CRP 39.28 (51.951) 3.19 (13.458) 0.000 ‡ **
Difference Ini-Fin CRP % 870.67 (1,794.80) 40.02 (157.75) 0.000 ‡ **
Difference final 2t CRP 36.23 (48.488) -1.31 (12.15) 0.000 ‡ **
Difference last CRP % 582.43 (1,638.27) 20.73 (112.93) 0.000 ‡ **
Leukocytes > 15 000 30/67 (44.8%) 19/135 (14.1%) 0.000 † **
Final leukocyte count 14,345.5 (5,498.0) 11,198.7 (3,493.9) 0.000 ‡ **
Difference Ini-Fin Leuko 3,150.5 (6,185.9) 665.8 (4,193) 0.000 ‡ **
Difference Ini-Fin Leuko % 37.78 (62.179) -1.055 (26.888) 0.000 ‡ **
Difference final 2 Leuko 3,529.8 (4,751.7) 503.6 (2,020) 0.000 ‡ **
Difference final 2 Leuko % 33.10 (50.914) 6.58 (18.402) 0.001 ‡ *
Max temp 37.1 (0.594) 36.7 (0.415) 0.006 ‡ *
Temp delivery day 36.72 (0.783) 36.81 (3.858) 0.087 ‡
Fever (≥ 37.8 °C) 7/48 (14.6%) 1/122 (0.82%) 0.001 § *
Max MHR 99.92 (11.56) 93.13 (13.55) 0.003 ‡ *
MHR delivery Day 93.57 (13.15) 82.69 (10.29) 0.000 ‡ **
Tachycardia (MHR > 100 bpm) 26/51 (51%) 19/111 (17.1%) 0.000 † **
Basal final MHR 141.69 (39.816) 145.34 (8.305) 0.641 ‡
Fetal tachycardia (FHR ≥ 160 bpm) 10/39 (25.6%) 6/95 (6.3%) 0.002 † **
Uterine pain 26/50 (52%) 10/120 (8.3%) 0.000 † **
Presence of contractions 42/49 (85.7%) 69/121 (57%) 0.000 † **