Table 1. Clinical aspects of the 37 cases of sporotrichosis in the nasal mucosa treated at the ENT outpatient clinic of the INI/FIOCRUZ (1998–2020).
| Case | Clinical form | Comorbidities | ENT signs and symptoms | Affected structure | Aspect | Intensity |
|---|---|---|---|---|---|---|
| 1 | Disseminated | HIV/AIDS, Tuberculosis | Nasal congestion / obstruction, Epistaxis, Presence / elimination of crusts | Diffuse | Mixed | Severe |
| 2 | Disseminated | Atopic dermatitis | Nasal congestion / obstruction, Epistaxis, Presence / elimination of crusts | Diffuse | Crusted | Severe |
| 3 | Disseminated cutaneous | Diabetes, Chronic renal failure, SAH, Deep vein thrombosis | Nasal congestion / obstruction | Diffuse | Infiltrative | Severe |
| 4 | Disseminated | HIV/AIDS | Rhinorrhea | Diffuse | Infiltrative | Severe |
| 5 | Disseminated cutaneous | Sarcoidosis | Bilateral involvement (RNF & LNF), Septal destruction/perforation, Mucosal infiltration, Presence/elimination of crusts, Ulceration | Septum | Mixed | Severe |
| 6 | Nasal mucosa (localized) | Nothing | Mucosal infiltration, Presence/elimination of crusts, Ulceration | Diffuse | Mixed | Severe |
| 7 | Nasal mucosa (localized) | Nothing | Presence/elimination of crusts, Rhinorrhea | Turbinates | Crusted | Severe |
| 8 | Disseminated | HIV/AIDS, Cytomegalovirus | Bilateral involvement (RNF & LNF), Nasal congestion/obstruction, Septal destruction/perforation, Pain, Mucosal infiltration, Presence/elimination of crusts, Ulceration | Diffuse | Mixed | Severe |
| 9 | Nasal mucosa (localized) | Nothing | Nasal congestion/obstruction, Pain | Turbinates | Infiltrative | Mild |
| 10 | Disseminated | HIV/AIDS | Bilateral involvement (RNF & LNF), Septal destruction/perforation, Presence/elimination of crusts, Ulceration | Diffuse | Crusted | Severe |
| 11 | Disseminated | Renal transplantation | Nasal congestion/obstruction, Presence/elimination of crusts | Turbinates | Crusted | Severe |
| 12 | Disseminated | Diabetes, SAH, Chronic renal failure | Bilateral involvement (RNF & LNF), Granulation, Mucosal infiltration | Diffuse | Mixed | Severe |
| 13 | Disseminated | Heart disease, SAH, HIV/AIDS | Hyperemia, Synechia | Diffuse | Infiltrative | Severe |
| 14 | Disseminated | HIV/AIDS | Bilateral involvement (RNF & LNF), Nasal congestion/obstruction, Mucosal infiltration, Presence/elimination of crusts, Rhinorrhea | Diffuse | Mixed | Severe |
| 15 | Nasal mucosa (localized) | Nothing | Nasal congestion/obstruction, Presence/elimination of crusts | Septum | Mixed | Severe |
| 16 | Disseminated | SAH | Bilateral involvement (RNF & LNF), Nasal congestion/obstruction, Presence/elimination of crusts | Diffuse | Mixed | Severe |
| 17 | Nasal mucosa (localized) | Nothing | Presence/elimination of crusts | Septum | Mixed | Severe |
| 18 | Disseminated | Nothing | Nasal congestion/obstruction, Epistaxis | Diffuse | Mixed | Severe |
| 19 | Nasal mucosa (localized) | Nothing | Pain, Presence/elimination of crusts | Turbinates | Mixed | Severe |
| 20 | Disseminated | HIV/AIDS, IRIS | Bilateral involvement, Nasal congestion/obstruction, Fever, Rhinorrhea | Diffuse | Mixed | Severe |
| 21 | Disseminated | Chemical dependence, Alcohol abuse, HIV/AIDS | Nasal congestion/obstruction, Dysphonia, Pain, Hemoptysis, Odynophonia, Presence/elimination of crusts, Cough | Diffuse | Mixed | Severe |
| 22 | Disseminated | Nothing | Pain, Epistaxis | Turbinates | Mixed | Moderate |
| 23 | Nasal mucosa (localized) | Nothing | Pain, Epistaxis, Rhinorrhea | Septum | Infiltrative | Moderate |
| 24 | Disseminated | Alcohol abuse | Granulation with microabscesses, Mucosal infiltration, Lymph node enlargement | Septum | Mixed | Moderate |
| 25 | Nasal mucosa (localized) | Nothing | Nasal congestion/obstruction, Lymph node enlargement, Presence/elimination of crusts | Turbinates | Mixed | Severe |
| 26 | Nasal mucosa (localized) | Nothing | Rhinorrhea | Septum | Infiltrative | Mild |
| 27 | Disseminated | HIV/AIDS | Bilateral involvement (RNF & LNF), Nasal congestion/obstruction, Epistaxis, Odynophagia, Presence/elimination of crusts | Diffuse | Mixed | Severe |
| 28 | Disseminated | HIV/AIDS, Cytomegalovirus | Bilateral involvement (RNF & LNF), Nasal congestion/obstruction, Septal destruction/perforation, Presence/elimination of crusts | Septum | Crusted | Severe |
| 29 | Nasal mucosa (localized) | Nothing | Mucosal infiltration, Presence/elimination of crusts, Ulceration | Septum | Mixed | Severe |
| 30 | Disseminated | Alcohol abuse | Granulation, Hyperemia, Rhinorrhea | Diffuse | Mixed | Severe |
| 31 | Disseminated cutaneous | Nothing | Presence/elimination of crusts | Diffuse | Mixed | Severe |
| 32 | Disseminated | SAH, HIV/AIDS | Nasal congestion/obstruction, Pain, Epistaxis, Mucosal infiltration, Pyrosis, Presence/elimination of crusts | Diffuse | Mixed | Severe |
| 33 | Disseminated | HIV/AIDS, Neurotoxoplasmosis | Septal destruction/perforation, Mucosal infiltration, Rhinorrhea | Septum | Mixed | Severe |
| 34 | Nasal mucosa (localized) | Heart disease | Granulation, Hyperemia, Mucosal infiltration | Septum | Mixed | Mild |
| 35 | Nasal mucosa (localized) | Respiratory disorders | Presence/elimination of crusts | Septum | Mixed | Severe |
| 36 | Nasal mucosa (localized) | Nothing | Pain, Granulation with microabscesses | Diffuse | Granular | Severe |
| 37 | Nasal mucosa (localized) | Nothing | Bilateral involvement (RNF & LNF), Hyperemia, Dryness | Diffuse | Mixed | Severe |
RNF: right nasal fossae; LNF: left nasal fossae; SAH: systemic arterial hypertension; HIV: human immunodeficiency virus; ENT: ear, nasal, and throat; IRIS: immune reconstitution inflammatory syndrome. Source: Electronic patient data system and Laboratory of Mycology database, both from INI/FIOCRUZ.