Table 3. Association of selected variables with the clinical form of 37 cases of sporotrichosis in the nasal mucosa treated at the ENT outpatient clinic at the INI/FIOCRUZ (1998–2020).
| Clinical form | |||
|---|---|---|---|
| Variable | Disseminated n (%) |
Nasal mucosa (localized) n (%) |
p-value |
| Sex | 0.037 | ||
| Female | 7 (30.4) | 10 (71.4) | |
| Male | 16 (69.6) | 4 (28.6) | |
| Probable transmission | 0.527 | ||
| Infected cat | 16 (69.6) | 12 (85.7) | |
| Others (non-cat) | 3 (13) | 0 (0) | |
| No epidemiological history | 4 (17.4) | 2 (14.3) | |
| Comorbidities | < 0.001 | ||
| No | 3 (13) | 12 (85.7) | |
| Yes | 20 (87) | 2 (14.3) | |
| Immunosuppression | < 0.001 | ||
| No | 5 (21.7) | 13 (92.9) | |
| Yes | 18 (78.3) | 1 (7.1) | |
| HIV | < 0.001 | ||
| No | 11 (47.8) | 14 (100) | |
| Yes | 12 (52.2) | 0 (0) | |
| Presence/elimination of crusts | 1 | ||
| No | 10 (43.5) | 6 (42.9) | |
| Yes | 13 (56.5) | 8 (57.1) | |
| Septal perforation | 0.135 | ||
| No | 18 (78.3) | 14 (100) | |
| Yes | 5 (21.7) | 0 (0) | |
| Nasal localization | 0.006 | ||
| Turbinates | 2 (8.7) | 4 (28.6) | |
| Diffuse | 17 (73.9) | 3 (21.4) | |
| Septum | 4 (17.4) | 7 (50) | |
| Number of affected nasal structure | 0.012 | ||
| Multiple | 16 (69.6) | 3 (21.4) | |
| Single | 7 (30.4) | 11 (78.6) | |
| Grouped appearance of the nasal lesion | 0.489 | ||
| Crusted | 4 (17.4) | 1 (7.1) | |
| Granular | 0 (0) | 1 (7.1) | |
| Infiltrative | 3 (13) | 3 (21.4) | |
| Mixed | 16 (69.6) | 9 (64.3) | |
| Intensity | 0.092 | ||
| Severe | 21 (91.3) | 10 (71.4) | |
| Moderate | 2 (8.7) | 1 (7.1) | |
| Mild | 0 (0) | 3 (21.4) | |
| Sporotrichosis outcome | 0.279 | ||
| Cure | 12 (52.2) | 12 (85.7) | |
| Under treatment | 2 (8.7) | 0 (0) | |
| Death | 2 (8.7) | 0 (0) | |
| Loss of follow-up | 7 (30.4) | 2 (14.3) | |
| Total | 23 (62.16) | 14 (37.84) | |
HIV: human immunodeficiency virus.