Table 3.
Baseline and 1 Year Post-Treatment Change in Health-Related Quality of Life and Symptom Severity
| Myomectomy, N = 446 (30.4%) | Hysterectomy, N = 741 (50.6%) | Endometrial ablation, N = 123 (8.4%) | Uterine artery embolization, N = 155 (10.6%) | |
|---|---|---|---|---|
| Quality of life at baseline mean (SD) | ||||
| HR-QoL score | 51.0 (25.4) | 44.3 (24.3) | 52.1 (23.2) | 40.6 (23.8) |
| Symptom severity | 50.3 (24.6) | 59.8 (24.1) | 47.4 (24.1) | 62.3 (24.4) |
| UFS-QOL domains | ||||
| Concern | 49.7 (33.4) | 38.3 (29.6) | 39.5 (27.8) | 35.0 (30.7) |
| Activity | 53.3 (28.8) | 45.5 (27.8) | 54.8 (27.3) | 43.3 (26.9) |
| Energy | 52.0 (27.8) | 45.6 (26.6) | 49.4 (24.4) | 41.0 (24.8) |
| Control | 50.8 (27.3) | 48.4 (26.9) | 60.3 (25.5) | 45.1 (27.4) |
| Self-conscious | 45.5 (31.5) | 42.2 (31.0) | 55.4 (31.4) | 35.2 (27.6) |
| Sexual function | 53.3 (34.0) | 44.8 (32.3) | 54.0 (33.8) | 42.8 (34.0) |
| Change in quality of life from baseline to 1 year mean (SD) | ||||
| Change in HR-QoL score improvement (+) ↑ | +36.6 (26.9) | +48.7 (26.2) | +32.6 (25.9) | +41.7 (27.4) |
| Change in symptom severity improvement (–) ↓ | –33.5 (25.6) | –51.9 (25.6) | –26.0 (30.1) | –42.2 (26.7) |
| Changes in UFS-QOL domains | ||||
| Concern | –37.0 (35.4) | –58.0 (31.9) | –45.4 (35.8) | –46.9 (34.4) |
| Activity | +37.2 (30.0) | +48.5 (30.1) | +32.2 (31.7) | +41.6 (31.3) |
| Energy | +35.1 (29.1) | +46.3 (28.8) | +32.7 (27.8) | +41.0 (28.8) |
| Control | +37.9 (29.0) | +45.3 (28.7) | +27.9 (26.2) | +40.5 (29.9) |
| Self-conscious | –36.7 (33.9) | –48.1 (32.4) | –24.8 (32.1) | –40.8 (32.5) |
| Sexual function | +33.7 (36.1) | +43.6 (36.0) | +28.0 (35.0) | +34.0 (37.5) |
Data are mean ± SD or % (n) unless otherwise specified.
HRQOL, health-related quality of life; UFS-QOL, uterine fibroid symptom quality of life.