TABLE 4.
Latent factor | PBMC subset | Module | Weight | r | p |
---|---|---|---|---|---|
1 | CD14+ | Black | 0.61 | 0.56 | 5.4×10−5 |
— | Turquoise | −0.66 | −0.74 | 8.1×10−9 | |
1 | TH1 | Yellow | 0.44 | 0.51 | 3.0×10−4 |
— | Green | −0.56 | −0.62 | 4.7×10−6 | |
1 | TH17 | Red | 0.45 | 0.55 | 9.7×10−5 |
— | Greenyellow | 0.63 | 0.69 | 1.4×10−7 | |
1 | TREG | Brown | −0.57 | −0.61 | 6.2×10−6 |
— | Green | 0.66 | 0.74 | 5.8×10−9 | |
— | Pink | 0.88 | 0.86 | 3.4×10−14 | |
1 | B | Red | 0.39 | 0.60 | 1.6×10−5 |
— | Black | 0.46 | 0.76 | 2.5×10−9 | |
4 | B | Black | −0.65 | −0.86 | 3.4×10−12 |
— | Brown | −0.91 | −0.91 | <2.2×10−16 | |
— | Turquoise | 0.93 | 0.94 | <2.2×10−16 |
Notes: Modules with the greatest loading on latent factors 1 or 4 are shown.
The weight measures how strongly the module relates to the latent factor (scale from −1 to 1).
r is the correlation coefficient between the modules and the latent factor, with the associated p-value.