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Probabilities of target attainment for 100% fT>MIC or 100% fT>4xMIC at trough concentrations <20 mg/L for intermittent infusion and <35 mg/L for continuous infusion. Simulation results in critically ill patients with three infusion times (0.5 h, 4 h, or continuous), various renal functions, and various MICs. The dosing interval was fixed to 8 h for intermittent infusion.
MIC, minimum inhibitory concentration.
