Table 1:
Patient Demographics
| Total (n=145) | Early Treatment (n=30) | No Early Treatment (n=115) | p-value | |
|---|---|---|---|---|
|
| ||||
| Recipient Age – Years (SD) | 50.7 (15.6) | 51.0 (11.1) | 51.4 (15.9) | 0.95 |
|
| ||||
| Donor Age – Years (SD) | 36.8 (14.1) | 37.2 (16.4) | 36.4 (13.6) | 0.54 |
|
| ||||
| Female Recipient (%) | 76 (52%) | 19 (63%) | 57 (50%) | 0.22 |
|
| ||||
| Bilateral Transplant (%) | 110 (76%) | 26 (87%) | 84 (73%) | 0.62 |
|
| ||||
| Diagnosis | 0.08 | |||
| COPD | 33 (23%) | 3 (10%) | 30 (26%) | |
| Cystic Fibrosis | 34 (23%) | 6 (20%) | 28 (24%) | |
| Interstitial Lung Disease | 60 (41%) | 17 (57%) | 43 (37%) | |
| Pulmonary Arterial Hypertension | 3 (2%) | 2 (7%) | 1 (1%) | |
| Sarcoidosis | 9 (6%) | 2 (7%) | 7 (6%) | |
| Other | 3 (2%) | 0 (0%) | 3 (3%) | |
| Re-transplantation | 3 (2%) | 0 (0%) | 3 (3%) | |
|
| ||||
| Race | 0.33 | |||
| White | 117 (81%) | 24 (80%) | 93 (81%) | |
| Black | 21 (14%) | 6 (20%) | 15 (13%) | |
| Asian | 4 (3%) | 0 (0%) | 4 (4%) | |
| Other | 3 (2%) | 0 (0%) | 2 (2%) | |
|
| ||||
| Total HLA Mismatches | 0.63 | |||
| 0 | 1 (1%) | 0 (0%) | 1 (1%) | |
| 1 | 0 (0%) | 0 (0%) | 0 (0%) | |
| 2 | 5 (3%) | 0 (0%) | 5 (4%) | |
| 3 | 13 (9%) | 3 (10%) | 10 (9%) | |
| 4 | 33 (23%) | 6 (20%) | 27 (23%) | |
| 5 | 47(32%) | 13 (43%) | 34 (30%) | |
| 6 | 46 (32%) | 8 (27%) | 38 (33%) | |
| HLA-A-Mismatch | 0.18 | |||
| 0 | 15 (10%) | 2 (7%) | 13 (11%) | |
| 1 | 45 (31%) | 6 (20%) | 39 (34%) | |
| 2 | 85 (59%) | 22 (73%) | 63 (55%) | |
| HLA-B-Mismatch | 0.25 | |||
| 0 | 5 (3%) | 0 (0%) | 5 (4%) | |
| 1 | 35 (24%) | 10 (33%) | 25 (22%) | |
| 2 | 105 (72%) | 20 (67%) | 85 (74%) | |
| HLA-DR-Mismatch | 0.02 | |||
| 0 | 9 (6%) | 0 (0%) | 9 (8%) | |
| 1 | 40 (28%) | 14 (47%) | 26 (23%) | |
| 2 | 96 (66%) | 16 (53%) | 80 (70%) | |