Table 1:

Summary of Participants in the Study

	FinnGen (discovery phase)			UKB (replication phase)
NDD	All	Female	Male	All	Female	Male
AD	9301	4079	5222	2342	1199	1143
ALS	483	181	302	357	209	148
dementia	16,499	6984	9515	2200	981	1219
MS	2182	1648	534	1349	985	364
PD	4235	1658	2577	2998	1106	1892
vascular	2335	778	1557	430	152	278
controls	309,154	173,746	135,408	96,390	48,919	47,471

Summary of participants analyzed in this study that includes over 400,000 samples across two national biobanks. In FinnGen, the control numbers listed below are the general population count (total); in the UKB these include exclusions described in the methods section such as concurrent neurodegenerative disease diagnoses.