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. Author manuscript; available in PMC: 2023 Apr 15.
Published in final edited form as: J Mol Biol. 2023 Feb 16;435(8):168010. doi: 10.1016/j.jmb.2023.168010

Figure 4.

Figure 4.

Effects of synthetic ligands on SHP2 allosteric regulation. (a) Effects of SHP099 on the interaction of the indicated SHP2 constructs with Mb13. (b) Effects of SH2-binding monobodies NSa1 and CS3. Data are shown in the same manner as in Figure 3.