Skip to main content
. 2023 Mar 24;14:1120250. doi: 10.3389/fpsyt.2023.1120250

Table 2.

Potential predictors of self-rated chronic fatigue syndrome onset by baseline fatigue severity.

Baseline No persistent fatigue n = 124,223 Persistent fatigue n = 10,217
No CFS n = 123,931 CFS onset n = 292 P value No CFS n = 10,025 CFS onset n = 192 P value Baseline CFS n = 1983
Females 58.6% 55.8% ns 72.6% 72.9% ns 69.1%
Married/cohabiting 80.4% 73.8% 0.007 73.7% 62.3% p = 0.001 68.4%
Off sick 3.1% 12.0% p < 0.001 10.0% 22.6% p < 0.001 20.2%
Low income 15.6% 25.0% p < 0.001 23.9% 34.0% p = 0.001 29.9%
Few years education 28.9% 42.9% p < 0.001 33.4% 48.1% p < 0.001 36.7%
Allergies 4+ 3.3% 4.8% p = 0.001 5.6% 8.3% ns 8.9%
Eczema 15.4% 21.2% 0.006 19% 23.4% ns 22.5%
Chronic sinusitis 5.6% 9.9% p = 0.001 10.1% 15.1% p = 0.022 20.1%
Stomach ulcer 2.6% 7.2% p < 0.001 4.4% 5.7% ns 7.7%
Gallstones 3.6% 6.8% p = 0.002 5.4% 5.7% ns 6.0%
COPD etc 5.1% 10.1% p < 0.001 8.6% 13.0% 0.033 12.9%
Chronic cystitis 1.9% 4.5% 0.001 3.9% 9.4% p < 0.001 6.9%
GERD 7.4% 14.4% p < 0.001 14.1% 26.0% p < 0.001 17.4%
Osteo-arthritis 7.4% 15.4% p < 0.001 8.8% 22.4% p < 0.001 15.2%
RA 2.1% 6.8% p < 0.001 3.9% 8.9% 0.001 5.8%
IBS 9.6% 20.5% p < 0.001 18.8% 30.7% p < 0.001 29.9%
FM 3.2% 7.9% p < 0.001 10.5% 27.1% p < 0.001 22.1%
PID 6.4% 12.0% p < 0.001 7.7% 9.9% ns 11.7%
RSI 2.2% 3.8% ns 3.2% 4.2 ns 4.7%
Migraine 18.5% 24.7% 0.006 28.0% 33.2% ns 33.9%
Paracetamol >50 pa 11.4% 18.9% p < 0.001 24.3% 35.9% p < 0.001 26.4%
No contact healthcare 1 year 7.9% 4.5% 0.030 3.0% 1.6% Ns 3.5%
Continuous variables
Mean age 44.2 (12.7) 47.9 (12.9) p < 0.001 40.9 (11.7) 45.8 (13.4) p < 0.001 45.2 (11.8)
Mean BMI 26.0 (4.3) 27.0 (4.7) p < 0.001 26.7 (5.3) 27.3 (5.5) ns 26.4 (4.9)
Life events and difficulties score 2.6 (1.7) 3.2 (1.8) p < 0.001 3.6 (1.6) 3.7 (1.5) ns 3.5 (1.6)
PSQI 4.0 (2.3) 5.8 (3.3) 5.2 (2.8) 7.3 (3.8) p < 0.001 5.6 (3.2)
SCL Somatization score 16.2 (4.5) 19.5 (5.6) p < 0.001 22.6 (6.7) 26.4 (7.8) p < 0.001 23.6 (7.8)
General health perception −0.12 (0.6) −0.52 (0.68) p < 0.001 −0.64 (0.73) −1.05 (0.7) p < 0.001 −0.80 (0.75)

FM, fibromyalgia; RA, rheumatoid arthritis; IBS, Irritable bowel syndrome; CFS, chronic fatigue syndrome; PID, prolapsed intervertebral disc; RSI, repetitive strain injury; GERD, gastroesophageal reflux disorder; PSQI, Pittsburgh Sleep Quality Inventory; SCL, Symptom checklist.