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. 2023 Mar 24;13:1096341. doi: 10.3389/fonc.2023.1096341

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Copyright © 2023 Xia, Li, Sun, Liu, Xu, An, Xu, Zhang, Zhong, Zeng, Ma, He, Zhang, Guan, Li and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential expression and prognostic value of TIGIT in KIRC. (A) TIGIT shows a significantly higher expression in non-paired KIRC tissues compared to the normal tissues. (B) TIGIT shows a significantly higher expression in paired KIRC tissues compared to the normal tissues. (C) High expression of TIGIT was associated with significantly poor overall survival in KIRC. (D) High expression of TIGIT was associated with significantly poor progression-free survival in KIRC. (E) High expression of TIGIT was associated with significantly poor disease-specific survival in KIRC. (F) There were no significant differences between patients with high or low expression of TIGIT in disease-free survival in KIRC. (G) Univariate Cox regression showed TIGIT a significant prognostic factor in KIRC. (H) Multivariate Cox regression of TIGIT in KIRC.