TABLE 1.
Demographic and clinical information of patients with Parkinson’s disease and healthy controls.
| EOPD | YCs | LOPD | OCs | P-value | |||
| EOPD VS. YCs | LOPD VS. OCs | EOPD VS. LOPD | |||||
| Gender (Female) | 28 (13) | 25 (18) | 22 (12) | 24 (12) | 0.06 | 0.758 | 0.569 |
| Agea | 47.25 ± 5.64 | 48.64 ± 2.87 | 58.22 ± 3.29 | 58.37 ± 3.80 | 0.258 | 0.889 | <0.001* |
| Age of Onsetb | 44.53 ± 4.84 | NA | 55.86 ± 3.41 | NA | NA | NA | <0.001* |
| Durationb, years | 2.78 ± 2.83 | NA | 2.35 ± 1.57 | NA | NA | NA | 0.929 |
| Educationa, years | 8.32 ± 3.38 | 9.04 ± 2.96 | 7.36 ± 4.39 | 7.22 ± 3.61 | 0.418 | 0.91 | 0.388 |
| Modified H-Y stageb | 1.68 ± 0.63 | NA | 1.95 ± 0.57 | NA | NA | NA | 0.146 |
| Total scores of UPDRSb | 26.25 ± 17.37 | NA | 34.59 ± 21.45 | NA | NA | NA | 0.137 |
| Scores of UPDRS-IIIb | 16.57 ± 11.55 | NA | 22.64 ± 15.50 | NA | NA | NA | 0.177 |
| MMSEb | 27.68 ± 2.07 | 28.08 ± 2.34 | 25.41 ± 2.71 | 25.87 ± 3.50 | 0.199 | 0.513 | 0.004* |
All data are presented as Median ± SD. EOPD, early-onset Parkinson’s disease; LOPD, late-onset Parkinson’s disease; YCs, young controls; OCs, old controls; H-Y stage, Hoehn and Yahr stage; UDPRS, Unified Parkinson’s Disease Rating Scale; MMSE, Mini-Mental State Examination; UDPRS-III, the third part of Unified Parkinson’s Disease Rating Scale. The chi-square test was performed for comparing gender differences between groups, Other data were compared between groups using two-sample t-test or Mann–Whitney U test.
aRepresents two-sample t-test.
bRepresents Mann–Whitney U test.
*Represent a significance at P < 0.05.