Table 2.
Descriptive data for patient reported outcome measures and neurocognitive assessments administered at VISIT 3.
| Domain | Group 1 (n = 8) | Group 2 (n = 10) | P-value | d (95% CI) |
|---|---|---|---|---|
| Patient reported outcome scores | ||||
| GAD-7 | 0.38 (1.06) | 2.6 (2.50)† | 0.03 | 1.11 (0.09, 2.10) |
| PHQ-9 | 0.63 (0.92) | 3.20 (1.25) | 0.09 | 0.85 (−0.14, 1.81) |
| PSQI | 6.5 (3.16) | 5.0 (2.94) | 0.31 | −0.49 (−1.43, 0.46) |
| Satisfaction with life scale | 28.9 (3.76) | 30.0 (3.50) | 0.52 | 0.31 (−0.65, 1.23) |
| Neurocognitive testing | ||||
| NIH flanker task | 104.4 (14.65) | 107.5 (5.02) | 0.54 | 0.30 (−0.64, 1.23) |
| NIH oral reading recognition | 111.8 (5.18) | 115.2 (2.82) | 0.09 | 0.86 (−0.13, 1.82) |
| NIH picture sequence memory | 107.9 (20.10) | 124.6 (15.10)† | 0.06 | 0.96 (−0.39, 1.93) |
| Rey auditory verbal learning test | 56.9 (8.44) | 60.1 (6.17) | 0.36 | 0.46 (−0.50, 1.38) |
| Rey auditory verbal learning test delayed | 11.5 (2.93) | 13.1 (2.02) | 0.19 | 0.65 (−0.32, 1.60) |
| Trail making A | 24.5 (10.13) | 18.2 (3.51) | 0.09 | −0.87 (−1.83, 0.12) |
| Trail making B | 48.6 (20.5) | 41.2 (9.57) | 0.32 | −0.83 (−0.48, −1.42) |
| Word choice test | 49.5 (0.93) | 49.8 (0.42) | 0.37 | 0.44 (−0.51, 1.37) |
†
represents a significant difference (p < 0.05) between groups.