Table 1A.

Cavalli case demographics and clinical characteristics stratified by sex and medulloblastoma subgroup.

	SHH		WNT		Group 3		Group 4		Chi-square p-value
	Females	Males	Females	Males	Females	Males	Females	Males
	N (%)	N (%)	N (%)	N (%)	N (%)	N (%)	N (%)	N (%)
Sex	86 (40.4)	127 (59.6)	38 (56.7)	29 (43.3)	36 (28.1)	92 (71.9)	89 (29.7)	211 (70.3)	0.00004
Age at diagnosis
0-<5	33 (40.2)	42 (34.1)	2 (5.7)	0 (0)	10 (28.6)	43 (50.6)	15 (17.2)	33 (16.4)
5-<10	15 (18.3)	23 (18.7)	10 (28.6)	10 (38.5)	19 (54.3)	30 (35.3)	47 (54.0)	86 (42.8)
10-<15	5 (6.1)	11 (8.9)	13 (37.1)	4 (15.4)	6 (17.1)	7 (8.2)	21 (24.1)	60 (29.9)
15-<20	8 (9.8)	11 (8.9)	8 (22.9)	4 (15.4)	0 (0.0)	1 (1.2)	2 (2.3)	18 (9.0)
≥20	21 (25.6)	36 (29.3)	2 (5.7)	8 (30.8)	0 (0.0)	4 (4.7)	2 (2.3)	4 (2.0)
missing	4	4	3	3	1	7	2	10
Fisher’s p-value		0.88		0.03		0.05		0.15
Histology
Classic	32 (44.4)	43 (42.2)	24 (88.9)	14 (70.0)	18 (64.3)	42 (67.7)	59 (81.9)	126 (78.3)
Desmoplastic	27 (37.5)	42 (41.2)	1 (3.7)	4 (20.0)	3 (10.7)	3 (4.8)	8 (11.1)	14 (8.7)
LCA	7 (9.7)	13 (12.7)	2 (7.4)	2 (10.0)	7 (25.0)	15 (24.2)	5 (6.9)	16 (9.9)
MBEN	6 (8.3)	4 (3.9)	0 (0.0)	0 (0.0)	0 (0.0)	2 (3.2)	0 (0.0)	5 (3.1)
missing	14	25	11	9	8	30	17	50
Fisher’s p-value		0.60		0.19		0.65		0.44
Metastasis
No	52 (82.5)	79 (85.9)	24 (92.3)	17 (85.0)	17 (60.7)	43 (60.6)	48 (63.2)	92 (58.2)
Yes	11 (17.5)	13 (14.1)	2 (7.7)	3 (15.0)	11 (39.3)	28 (39.4)	28 (36.8)	66 (41.8)
missing	23	23	23	23	23	23	23	23
Fisher’s p-value		0.65		0.64		1.00		0.48
Vital Status
Alive	48 (70.6)	87 (84.5)	33 (97.1)	24 (92.3)	19 (67.9)	44 (58.7)	59 (72.8)	121 (70.8)
Deceased	20 (29.4)	16 (15.5)	1 (2.9)	2 (7.7)	9 (32.1)	31 (41.3)	22 (27.2)	50 (29.2)
missing	18	24	4	3	8	17	8	40
Fisher’s p-value		0.036		0.57		0.50		0.77

Statistically significant p-values (<0.05) are in bold.