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. 2023 Feb 3;120(5):71–80. doi: 10.3238/arztebl.m2022.0406

eTable 3. Current key studies on the surgical treatment of stress urinary incontinence in women.

n Comparison Study design Primary endpoint Results [95% CI] Adverse events
Study: Schellart et al. (2014) (e23)
193 MiniArc vs. TOT randomized, non-blinded, non-inferiority design Improved PGI-I score MiniArc is not inferior to TOT after 3 years 13% serious adverse events with MiniArc, 11% with TOT
Study: Itkonen Freitas et al. (2022) (e24)
223 TVT vs. polyacrylamide hydrogel
(bulkamide)
randomized, non-blinded, non-inferiority design patient satisfaction questionnaire bulkamide is inferior to TVT at 3 years* 43.5% complication rate for DVT, 24% for bulkamide*
Study: Dogan et al. (2018) (e25)
201 needle-free single-incision muscular sling (SIMS) vs. TOT randomized, non-blinded, single-center negative cough test SIMS and TOT are comparably effective at 2 years (90% vs. 85% cure) 13% complication rate with TOT, 7% with SIMS* (SIMS significantly fewer symptoms)
Study: Holdø et al. (2017) (e26)
307 Burch colposuspension vs. TVT non-randomized, non-simultaneous case series comparison recurrent incontinence revision rates at 12 years, 11%
(colposuspension) vs. 2% (TVT)*
16% complication rate with colposuspension vs. 11% with TVT
Study: Lau et al. (2013) (e27)
100 TOT vs. TOT after vaginal prolapse net (Prolift) non-randomized, prospective case series comparison negative cough test at 3–6 months, 86% cure rate for TOT versus 62% for TOT after vaginal mesh* 9% complication rate with TOT after vaginal mesh vs. 0% with TOT*
Study: Ward KL (2008) (e28)
344 Burch colposuspension vs. TVT prospectively randomized, non-blinded multicenter trial negative 1 hour pad test at 5 years, 81% cure rate for colposuspension vs. 90% for TVT more recto- and enteroceles with colposuspension*, complication rate 11% with colposuspension vs. 8% with TVT
Study: Karmakar (2017) (e29)
341 transobturator tape, inside-out vs. outside-in postal follow-up of a randomized, controlled trial patient satisfaction, measured with the PGI-I 71.6 % satisfaction and 14% improvement in 7.96% new urinary incontinence surgery required,
4.5% erosion rate,
4.32% pain,
in 1.4% therapy required
Study: Dejene et al. (2022) (e30)
334 601 follow-up of up to 15 years cohort study Frequency of of surgical revisions at 10 years, 6.9%;
at 15 years, 7.9%
increased risk of surgical revision,
in women aged
18–29 vs. ≥ 70 years
approx. 50 % of surgical revisions necessitated by tape erosion

PGI-I, Patient Global Impression Incontinence; TOT, transobturator tape; TVT, tension-free vaginal tape“ (retropubic);

*p ≤ 0.05